Description

Irinotel 100 mg Injection – Effective Chemotherapy for Colorectal Cancer

Irinotel 100 mg Injection is a powerful prescription-based anticancer medication used in the treatment of colorectal cancers, including cancer of the colon and rectum. It belongs to a class of chemotherapy drugs known as topoisomerase I inhibitors, which help to stop or slow the growth of cancer cells in the body.

This medicine is most often used in combination with other anticancer drugs during chemotherapy regimens to enhance its effectiveness. This injection is administered intravenously by a trained medical professional in a clinical setting such as a hospital or chemotherapy center.

What is Irinotel 100?

This Injection contains Irinotecan Hydrochloride as its active ingredient. Irinotecan is derived from camptothecin, a natural compound that interferes with the enzyme topoisomerase I. This enzyme is necessary for DNA replication and cell division, making This injection a highly effective drug for stopping the spread of cancer cells.

This medication is primarily used in the treatment of advanced or metastatic colorectal cancer, often when other treatments have failed or are no longer effective.

Medical Uses of Irinotel 100

1. Colorectal Cancer (Colon and Rectal Cancer)

This injection is widely used as a first-line or second-line therapy for metastatic colorectal cancer. It is often combined with other chemotherapy agents like 5-fluorouracil (5-FU) and leucovorin, especially in protocols such as FOLFIRI.

2. Off-label Uses

In some cases, oncologists may use this injection off-label for treating other cancers such as:

• Small cell lung cancer

• Ovarian cancer

• Pancreatic cancer

• Gastroesophageal junction cancer
  (Note: Off-label use should only be considered under a specialist’s supervision.)

How Irinotel 100 Works

Irinotel 100 works by inhibiting the activity of topoisomerase I, an enzyme that helps cancer cells duplicate their DNA during cell division. By blocking this enzyme, This injection causes DNA damage, preventing the cells from dividing and leading to cancer cell death.

This mechanism targets fast-growing cancer cells while sparing some normal tissues, making this injection a targeted cytotoxic therapy.

Benefits of Irinotel 100

• Slows tumor growth in colorectal cancer

• Can be used as monotherapy or in combination regimens

• Suitable for patients with recurrence or metastasis

• Administered under medical supervision for maximum safety

• Targets cancer cells at the DNA replication level

Dosage and Administration

Important: Irinotel 100 should only be administered by a trained medical professional.

• Form: Intravenous injection

• Strength: 100 mg / 5 ml vial

• Route: IV infusion over 90 minutes

• Schedule: Every 2 or 3 weeks, depending on treatment protocol

The exact dosage and treatment duration will be determined by your oncologist based on:

• Your body surface area (BSA)

• Type and stage of cancer

• Overall health and response to treatment

• Whether it’s combined with other chemotherapy drugs

Possible Side Effects of Irinotel 100

While Irinotel 100 is effective in treating cancer, it may cause side effects. These vary from person to person and can range from mild to severe.

Common Side Effects:

• Diarrhea (early-onset or delayed-onset)

• Nausea and vomiting

• Low white blood cell count (neutropenia)

• Fatigue

• Hair loss

• Abdominal cramps

Serious Side Effects (seek immediate medical attention):

• Severe dehydration from diarrhea

• Signs of infection (fever, chills)

• Liver toxicity

• Shortness of breath

• Mouth sores (mucositis)

Tip: Anti-diarrheal medications such as loperamide are often prescribed alongside Irinotel 100 to manage diarrhea effectively.

Precautions Before Taking Irinotel 100

Inform your doctor before taking Irinotel 100 mg Injection if you:

• Are pregnant or planning pregnancy

• Are breastfeeding

• Have liver or kidney disease

• Have a history of intestinal blockage or bowel issues

• Are using other medications (including herbal supplements)

Pregnancy & Breastfeeding Warnings

• Pregnancy: Not recommended. Irinotel 100 may cause harm to the fetus. Use reliable contraception during and after treatment.

• Breastfeeding: Avoid breastfeeding while receiving this medication, as it may pass into breast milk and harm the baby.

Diet and Lifestyle Advice

• Stay well-hydrated to manage side effects like diarrhea

• Eat small, frequent meals to reduce nausea

• Avoid raw or uncooked food to minimize infection risk

• Follow your oncologist’s dietary recommendations

• Maintain personal hygiene and handwashing to prevent infections

Storage Instructions for Irinotel 100

• Store in a refrigerated environment (2°C to 8°C)

• Do not freeze

• Keep away from light and moisture

• Keep out of reach of children and pets

• Dispose of unused medicine responsibly, as per local guidelines

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Frequently Asked Questions (FAQs)

Q1. What is this injection used for?

A: Irinotel 100 is used for treating colon and rectal cancers, especially in advanced or metastatic stages.

Q2. Is this injection a chemotherapy drug?

A: Yes, it is a cytotoxic chemotherapy drug that inhibits DNA replication in cancer cells.

Q3. How is this injection administered?

A: It is given as an IV infusion by a qualified healthcare professional.

Q4. Can I take this injection at home?

A: No, it must be administered in a clinical or hospital setting under medical supervision.

Q5. What should I do if I miss a dose?

A: Since Irinotel is administered by a doctor, your treatment schedule will be managed by your medical team. Don’t self-administer or skip appointments.